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length of follow up after first providing information on smoking status was 22.9 years (20.4 for men and 24.6 for women). In the late 1960s, 74% of men and 13% of women reported that they were current smokers, and 13% of men and 2% of women reported that they were former smokers (table 2). In later survey periods, the percentages of current smokers decreased in both sexes and the percentages of former smokers increased. Among current and formers smokers, 25% of men (5842 individuals) and 5% of women (357 individuals) reported that they had started smoking before the age of 20.

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1. Sally Hopewell (Centre for Statistics in Medicine, University of Oxford, Wolfson College, Oxford, UK ) 3. Kenneth F Schulz (Family Health International, Research Triangle Park, NC 27709, USA ) 4. Victor Montori (UK Knowledge and Encounter Research Unit, Mayo Clinic, Rochester, MN, USA ) 5. Peter C G?tzsche (The Nordic Cochrane Centre, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark ) 6. P J Devereaux (McMaster University Health Sciences Centre, Hamilton, Canada ) 7. Diana Elbourne (Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London, UK ) 8. Matthias Egger (Institute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland ) 9. Douglas G Altman (Centre for Statistics in Medicine, https://www.poloralphlaurenaustralia.nu University of Oxford, Wolfson College, Oxford, UK )Overwhelming evidence shows the quality of reporting of randomised controlled trials (RCTs) is not optimal. Without transparent reporting, readers cannot judge the reliability and validity of trial findings nor extract information for systematic reviews. Recent methodological analyses indicate that inadequate reporting and design are associated with biased estimates of treatment effects. Such systematic error is seriously damaging to RCTs, which are considered the gold standard for evaluating interventions because of their ability to minimise or avoid bias.

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